A KIDNEY-TARGETED NANOPARTICLE TO AUGMENT RENAL LYMPHATIC DENSITY DECREASES BLOOD PRESSURE IN HYPERTENSIVE MICE

A Kidney-Targeted Nanoparticle to Augment Renal Lymphatic Density Decreases Blood Pressure in Hypertensive Mice

Chronic interstitial inflammation and renal infiltration of activated immune cells play an integral role in hypertension.Lymphatics regulate inflammation through clearance of immune cells and excess interstitial fluid.Previously, we demonstrated increasing renal lymphangiogenesis prevents hypertension in mice.We hypothesized that targeted nanoparti

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bHLH Transcription Factor NtMYC2a Regulates Carbohydrate Metabolism during the Pollen Development of Tobacco (Nicotiana tabacum L. cv. TN90)

Basic helix-loop-helix (bHLH) transcription factor MYC2 regulates plant growth and development in many aspects through the jasmonic acid (JA) signaling pathway, while the role of MYC2 in plant carbohydrate metabolism has not been reported.Here, we generated NtMYC2a-overexpressing (NtMYC2a-OE) and RNA-interference-mediated knockdown (NtMYC2a-RI) tra

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